Events during September 2023

Effects of direct thrombin inhibitors [dabigatran/argatroban/bivalirudin] on tests of haemostasis

Join your network workforce leads/practice educators for a solution focused discussion around workforce challenges. Find out about current education and development opportunities with specific emphasis on support workers, advanced clinical practice and leadership. We welcome your participation in helping to shape the future of your pathology workforce.

You are invited by the speakers to complete this online form before the presentation

Idiopathic Membranous Nephropathy: PLA2 and beyond

Newborn screening (NBS) is an essential public health strategy aimed at identifying newborn babies that are affected by certain genetic, metabolic and infectious conditions. NBS enables the early detection and management of several congenital disorders, which if left untreated, may lead to mental retardation and/or death. Early diagnosis and instigation of treatment, along with appropriate long-term care help ensure normal growth and development of the affected individual.

The Sheffield Regional NBS Laboratory is one of the largest newborn screening laboratories in the UK testing around 65,000 newborn bloodspot samples per year and has been an integral part of routine newborn care for the region of South Yorkshire, Lincolnshire and East Midlands. Newborn screening in the United Kingdom now includes screening for 10 conditions including multiple metabolic, haemoglobinopathies and only recently severe combined immunodeficiency - all detectable though multiplex laboratory procedures.

This presentation will briefly review the implementation of newborn screening in the region, including a brief history and justification for newborn screening, laboratory detection and diagnosis of the screening condition, the referral pathway/notification to a regional consultant paediatrician for initiation of treatment of the condition/follow up testing and conclude with a case study.

This presentation will focus on the PD-L1 clones used for the different indications, acceptable and not acceptable tests, and the importance of ideal controls.

Delegates attending this presentation will:

Receive an overview of PD-L1 EQA assessments carried out by UK NEQAS ICC & ISH
Gain a better understanding of the UK NEQAS PD-L1 schemes and how assessments are carried out.

The requirement of extensive and complex testing on cytology samples is widely and routinely recognised. ROSE performed by scientists in the clinical setting provides a standardised, clinically effective, reproducible methodology for a variety of anatomical sites, some of which cytology is the only modality for sampling.

Real-time adequacy assessment eliminates the need for more invasive or repeat procedures by ensuring sufficient cell yield is obtained to conduct all the tests required for ancillary and molecular testing. This streamlines the patient pathway by reducing the referral to treatment time and reduces waiting list pressures, resulting in cost reduction for healthcare trusts and improved patient care and outcomes.

The presentation will explore the new IBMS ROSE qualification with the aim to inspire scientists to become skilled in ROSE.

The presentation provides an overview on the technology and analytical performance of a new true molecular point of care testing system without need for upfront specimen preparation, and the potential benefits resulting from its use at the point of care. The presentation also discusses key aspects to be considered prior to implementation at the point of care

This presentation will include how her career progressed to a Point of Care Testing (POCT) role in the Wales Specialist Virology Centre. It will also cover what POCT is; the method of testing, who gets tested and why POCT is crucial in the efforts to achieve the WHO initiative to eliminate Hepatitis C in Wales.

Examples of what a day-in-the-life of a "POCT-er" consists of: mass screening projects, case studies, what has been learnt from testing in prison and in the community (homeless shelters and substance misuse services). The future of POCT: what's on the horizon?

Who lives in a papaya under the sea? SpongeBob Alloadsorption Pants! A Transfusion Laboratory Perspective of AIHA

The effects of long COVID on coagulopathy